Rustem Pasha Madrasah was built by Mimar Sinan with Rüstem Pasha ‘s support who is the son in law of Kanuni Sultan Suleyman and became grand veziriate of Suleyman in later periods between 1544-1533 and 1533-1561.
Although the date in which the madrasah was established is commonly known as being 1547; in its inscription the date is shown to be 1550. The madrasah has architectual qualities that are highly regarded and which stand out as unique from its surroundings.
Mimar Sinan, in this particular monument, used a different style than the other madrasahs in Istanbul with the repetition of the octagonal yard system that was used in Kapi Agasi Madrasah in Amasya in 1488. The structure; which has a square shape in the outside has 24 rooms inside that had been placed behind surrounding octagonal porches. The plan of the corner rooms that enables the passing from the square system to the octagon system is only tried in this madrasah by Sinan.
Rustem Pasha Madrasah is an edifice in terms of its size, style and arhitectural design that is built for the name of sultans. Like most other Ottoman monuments, its outer walls are composed of limestone.
The construction that was used as the madrasah until the 19th century in the Ottoman period was also used as an orphanage and as a college dormitory in 20th century. It was restored in the years of 1843,1868,1893,1903 and 1916 . It was recently restored by the Fatih Municipality in 2009 and in 2012, and it was assigned to the Istanbul Foundation for Science and Culture to be used for cultural and scholarly purposes. It now has 4 rooms which are each part of a permanent museum to show historical documents about Said Nursi and his book collection – the “Risale-i Nur”.